Sex-related differences in left ventricular assist device utilization and outcomes: results from the PCHF-VAD registry.

ABSTRACT:

Aims

Data on sex and left ventricular assist device (LVAD) utilization and outcomes have been conflicting and mostly confined to US studies incorporating older devices. This study aimed to investigate sex-related differences in LVAD utilization and outcomes in a contemporary European LVAD cohort.

Methods and results

This analysis is part of the multicentre PCHF-VAD registry studying continuous-flow LVAD patients. The primary outcome was all-cause mortality. Secondary outcomes included ventricular arrhythmias, right ventricular failure, bleeding, thromboembolism, and the haemocompatibility score. Multivariable Cox regression models were used to assess associations between sex and outcomes. Overall, 457 men (81%) and 105 women (19%) were analysed. At LVAD implant, women were m

SUBMITTER: Radhoe SP 

PROVIDER: S-EPMC10053365 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature