Machine learning unifies flexibility and efficiency of spinodal structure generation for stochastic biomaterial design.

ABSTRACT: Porous biomaterials design for bone repair is still largely limited to regular structures (e.g. rod-based lattices), due to their easy parameterization and high controllability. The capability of designing stochastic structure can redefine the boundary of our explorable structure-property space for synthesizing next-generation biomaterials. We hereby propose a convolutional neural network (CNN) approach for efficient generation and design of spinodal structure-an intriguing structure with stochastic yet interconnected, smooth, and constant pore channel conducive to bio-transport. Our CNN-based approach simultaneously possesses the tremendous flexibility of physics-based model in generating various spinodal structures (e.g. periodic, anisotropic, gradient, and arbitrarily large ones) and co

SUBMITTER: Wang Z 

PROVIDER: S-EPMC10070414 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature