Novel N(SCF₃)(CF₃)-amines: synthesis, scalability and stability.

ABSTRACT: We disclosed herein a straightforward strategy for the synthesis of unprecedented N-((trifluoromethyl)thio), N-(trifluoromethyl) amines using a combination of isothiocyanates with a fluoride source and an electrophilic trifluoromethylthiolation reagent. More interestingly, the scalability of the methodology has been demonstrated and the stability of the new motif has been studied.

SUBMITTER: Yang Y 

PROVIDER: S-EPMC10074438 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature