Depression and anxiety in patients with uveal melanoma undergoing curative proton treatment-A prospective study.

ABSTRACT:

Objective

We prospectively addressed whether patient characteristics, oncological outcomes, or metastatic risk impacted depression and anxiety in patients undergoing curative proton treatment for uveal melanoma (UM).

Methods

We assessed patient-reported outcomes regarding anxiety (GAD-7) before and 2 years after proton therapy and depression (PHQ-9) before, 1, and 2 years after proton therapy. We performed descriptive statistics and used linear mixed effect modeling to analyze how the oncological outcome and baseline characteristics impacted anxiety and depression scores.

Results

Of 130 (65 female) patients included, six developed metastatic disease and three died during the 2-year follow-up. The mean anxiety declined from 5.86 (SE = 0.56) at baseline to 3.74 (SE = 0.

SUBMITTER: Rabsahl C 

PROVIDER: S-EPMC10075284 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature