Long-term follow-up result of antithyroid drug treatment of Graves' hyperthyroidism in a large cohort.

ABSTRACT:

Objective

This study evaluated the efficacy of antithyroid drugs (ATDs) and risk factors associated with the recurrence of Graves' hyperthyroidism using a comprehensive retrospective cohort.

Methods

We included 1829 patients newly diagnosed with Graves' hyperthyroidism, with sufficient follow-up data. Clinical outcomes of the patients and risk factors associated with recurrence-free survival, including the changes in thyrotropin receptor antibody, were evaluated.

Results

The median age of the patients was 44.5 years, and 69% were female. Among the patients, 1235 had a chance to withdraw ATD after a median of 23 (interquartile range (IQR) 17.0-35.5) months of treatment. The first remission rate was 55.6% during a median of 72.7 months of follow-up. After the first recu

SUBMITTER: Jin M 

PROVIDER: S-EPMC10083656 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature