Plantar osteochondral fragments in young Standardbreds are associated with minimal joint inflammation at the time of surgical removal.

ABSTRACT:

Background

Plantar osteochondral fragments (POF) are common but their effect on joint health of young Standardbreds in race training is largely unknown.

Objectives

Evaluate the inflammatory effects of POF in metatarsophalangeal joints of young Standardbreds as a step towards developing evidence-based recommendations for surgical removal.

Study design

Cohort study.

Methods

Forty-nine Standardbred horses (age 11-33 months) presented for surgical removal of POF from 56 metatarsophalangeal joints. Synovial tissue collected at arthroscopy was subjected to histopathology. IL-1β, TNF-α, and PGE-2 were measured in synovial fluid using ELISA. Digital arthroscopy images were scored for inflammation. Racing performance data were retrieved from a public database.

Result

SUBMITTER: McCoy AM 

PROVIDER: S-EPMC10083909 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature