Fasting increases investment in soma upon refeeding at the cost of gamete quality in zebrafish.

ABSTRACT: Fasting increases lifespan in invertebrates, improves biomarkers of health in vertebrates and is increasingly proposed as a promising route to improve human health. Nevertheless, little is known about how fasted animals use resources upon refeeding, and how such decisions affect putative trade-offs between somatic growth and repair, reproduction and gamete quality. Such fasting-induced trade-offs are based on strong theoretical foundations and have been recently discovered in invertebrates, but the data on vertebrates are lacking. Here, we report that fasted female zebrafish, Danio rerio, increase investment in soma upon refeeding, but it comes at a cost of egg quality. Specifically, an increase in fin regrowth was accompanied by a reduction in 24 h post-fertilization offspring surv

SUBMITTER: Ivimey-Cook ER 

PROVIDER: S-EPMC10089719 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature