Biology and management of lobular endocervical glandular hyperplasia.

ABSTRACT:

Aim

Lobular endocervical glandular hyperplasia (LEGH) is a multicystic proliferative disorder of the uterine cervix. The aim of this review was to clarify the current understanding of this unique tumor.

Method

This article reviews the chronological progress of research regarding clinico-pathological and genetic aspects of LEGH and related cervical cystic diseases such as Nabothian cyst and adenocarcinoma of gastric type (GAS), using the literature and data from our institute. We also describe clinical management including preoperative diagnosis and adequate surgical/expectant treatment based on the biological features.

Results

Recent studies revealed several unique aspects of LEGH, that is, (i) production of gastric mucin, (ii) symptomatic and histological similarity

SUBMITTER: Miyamoto T 

PROVIDER: S-EPMC10092153 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature