Exploration of the relationships between clinical traits and functional connectivity based on surface morphology abnormalities in bulimia nervosa.

ABSTRACT:

Background

Bulimia nervosa is a recurrent eating disorder with uncertain pathogenesis. Recently, there has been growing interest in using neuroimaging techniques to explore brain structural and functional alterations in bulimia nervosa, but the findings of previous studies have a great number of inconsistencies.

Methods

Here, we collected anatomical and resting-state functional magnetic resonance imaging data from 43 bulimia nervosa patients and 34 matched healthy controls (HCs). We applied a surface-based morphology analysis to explore brain cortical morphology differences and a novel surface-based functional connectivity (FC) analysis to investigate functional abnormalities. Principal component analysis was performed to analyze the behavioral data of the participants. We f

SUBMITTER: Li W 

PROVIDER: S-EPMC10097070 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature