Phosphatidic acid-regulated SOS2 controls sodium and potassium homeostasis in Arabidopsis under salt stress.

ABSTRACT: The maintenance of sodium/potassium (Na⁺ /K⁺ ) homeostasis in plant cells is essential for salt tolerance. Plants export excess Na⁺ out of cells mainly through the Salt Overly Sensitive (SOS) pathway, activated by a calcium signal; however, it is unknown whether other signals regulate the SOS pathway and how K⁺ uptake is regulated under salt stress. Phosphatidic acid (PA) is emerging as a lipid signaling molecule that modulates cellular processes in development and the response to stimuli. Here, we show that PA binds to the residue Lys57 in SOS2, a core member of the SOS pathway, under salt stress, promoting the activity and plasma membrane localization of SOS2, which activates the Na⁺ /H⁺ antiporter SOS1 to promote the Na

SUBMITTER: Li J 

PROVIDER: S-EPMC10106984 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature