Ontology highlight
ABSTRACT:
SUBMITTER: Keniry A
PROVIDER: S-EPMC10112917 | biostudies-literature | 2022 Nov
REPOSITORIES: biostudies-literature
Development (Cambridge, England) 20221128 22
Female mouse embryonic stem cells (mESCs) present differently from male mESCs in several fundamental ways; however, complications with their in vitro culture have resulted in an under-representation of female mESCs in the literature. Recent studies show that the second X chromosome in female, and more specifically the transcriptional activity from both of these chromosomes due to absent X chromosome inactivation, sets female and male mESCs apart. To avoid this undesirable state, female mESCs in ...[more]