Updated Percentiles for the University of Pennsylvania Smell Identification Test in Adults 50 Years of Age and Older.

ABSTRACT:

Background and objectives

The University of Pennsylvania Smell Identification Test (UPSIT) is commonly used to assess olfaction and screen for early detection of disorders including Parkinson (PD) and Alzheimer disease. Our objective was to develop updated percentiles, based on substantially larger samples than previous norms, to more finely discriminate age- and sex-specific UPSIT performance among ≥50-year-old adults who may be candidates for studies of prodromal neurodegenerative diseases.

Methods

The UPSIT was administered cross-sectionally to participants recruited between 2007-2010 and 2013-2015 for the Parkinson Associated Risk Syndrome (PARS) and Parkinson's Progression Markers Initiative (PPMI) cohort studies, respectively. Exclusion criteria included age <50 years

SUBMITTER: Brumm MC 

PROVIDER: S-EPMC10115503 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature