In vitro PCR verification that lysozyme inhibits nucleic acid replication and transcription.
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ABSTRACT:
SUBMITTER: Liu L
PROVIDER: S-EPMC10115842 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
Publications
In vitro PCR verification that lysozyme inhibits nucleic acid replication and transcription.
Liu Lu L Jia Xu X Zhao Xiaoyang X Li Ting T Luo Ziren Z Deng Ranxi R Peng Bijia B Mao Danting D Liu Hong H Zheng Qian Q
Scientific reports 20230419 1
Lysozyme can kill bacteria by its enzymatic activity or through a mechanism involving its cationic nature, which can facilitate electrostatic interactions with the viral capsid, the negatively charged parts of nucleic acids, and polymerase, so binding to nucleic acids may be another biological function of lysozyme. Here, PCR was used as a research tool to detect the effects of lysozyme on the replication and transcription of nucleic acids after treatment in different ways. We found that lysozyme ...[more]
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