Factors associated with unrecognized cirrhosis in patients with hepatocellular carcinoma.

ABSTRACT:

Background/aims

Cirrhosis is the most important risk factor of hepatocellular carcinoma (HCC), and patients with cirrhosis are recommended to receive semiannual surveillance for early HCC detection. However, early cirrhosis is often asymptomatic and can go undiagnosed for years, leading to underuse of HCC surveillance in clinical practice. We characterized the frequency and associated factors of unrecognized cirrhosis in a national sample of patients with HCC from the United States.

Methods

HCC patients aged 68 years and older, diagnosed during 2011 to 2015 were included from the SEERMedicare Linked Database. If cirrhosis was diagnosed within 6 months immediately preceding HCC diagnosis or after HCC diagnosis, cases were categorized as unrecognized cirrhosis. Factors associa

SUBMITTER: Lee YT 

PROVIDER: S-EPMC10121289 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature