Comparison of alternative splicing (AS) events in adipose tissue of polled dorset versus small tail han sheep.

ABSTRACT:

Background

During the alternative splicing (AS), the exons of primary transcripts are spliced in various arrangements, resulting in structurally and functionally distinct mRNAs and proteins. This study aimed to examine genes with AS events from Small Tail Han sheep and Dorset sheep to explore the mechanism of adipose developments.

Methods

This study identified the genes with AS events in adipose tissues of two different sheep with next-generation sequencing. In this paper, genes with significantly different AS events were performed gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses.

Results

364 genes with 411 A S events showed significant differences in adipose tissues between the two breeds; 108 genes with 120 A S events were ex

SUBMITTER: Miao X 

PROVIDER: S-EPMC10121611 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature