Whole-brain diffusion tensor imaging predicts 6-month functional outcome in acute intracerebral haemorrhage.

ABSTRACT:

Introduction

Small vessel disease (SVD) causes most spontaneous intracerebral haemorrhage (ICH) and is associated with widespread microstructural brain tissue disruption, which can be quantified via diffusion tensor imaging (DTI) metrics: mean diffusivity (MD) and fractional anisotropy (FA). Little is known about the impact of whole-brain microstructural alterations after SVD-related ICH. We aimed to investigate: (1) association between whole-brain DTI metrics and functional outcome after ICH; and (2) predictive ability of these metrics compared to the pre-existing ICH score.

Methods

Sixty-eight patients (38.2% lobar) were retrospectively included. We assessed whole-brain DTI metrics (obtained within 5 days after ICH) in cortical and deep grey matter and white matter. We use

SUBMITTER: Schwarz G 

PROVIDER: S-EPMC10129992 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature