Risk factors and vectors for SARS-CoV-2 household transmission: a prospective, longitudinal cohort study.

ABSTRACT:

Background

Despite circumstantial evidence for aerosol and fomite spread of SARS-CoV-2, empirical data linking either pathway with transmission are scarce. Here we aimed to assess whether the presence of SARS-CoV-2 on frequently-touched surfaces and residents' hands was a predictor of SARS-CoV-2 household transmission.

Methods

In this longitudinal cohort study, during the pre-alpha (September to December, 2020) and alpha (B.1.1.7; December, 2020, to April, 2021) SARS-CoV-2 variant waves, we prospectively recruited contacts from households exposed to newly diagnosed COVID-19 primary cases, in London, UK. To maximally capture transmission events, contacts were recruited regardless of symptom status and serially tested for SARS-CoV-2 infection by RT-PCR on upper respiratory tra

SUBMITTER: Derqui N 

PROVIDER: S-EPMC10132910 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature