The therapeutic benefit of upgrade to cardiac resynchronization therapy in patients with pacing-induced cardiomyopathy.

ABSTRACT:

Background

Pacing-induced cardiomyopathy (PICM) is an important cause of heart failure in patients with a right ventricular pacing burden. Recent evidence suggests that an upgrade to cardiac resynchronization therapy (CRT) may confer benefit in PICM.

Objective

To assess the extent and identify predictors of improvement following upgrade to CRT in patients with PICM.

Methods

We retrospectively analyzed 43 patients undergoing CRT upgrade for PICM over the 10-year period of 2011 to 2021 at our center. All patients with PICM who underwent device upgrade from a dual- or single-chamber ventricular pacemaker to CRT were included. PICM was defined as a decrease of ≥10% in left ventricular ejection fraction (LVEF), resulting in an LVEF <50% among patients with ≥20% Right ventr

SUBMITTER: Kerley RN 

PROVIDER: S-EPMC10134389 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature