ClotFoam: An Open-Source Framework to Simulate Blood Clot Formation Under Arterial Flow.
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ABSTRACT:
SUBMITTER: Montgomery D
PROVIDER: S-EPMC10153289 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature
Publications
clotFoam: An Open-Source Framework to Simulate Blood Clot Formation Under Arterial Flow.
Montgomery David D Municchi Federico F Leiderman Karin K
ArXiv 20230801
Blood clotting involves the coupled processes of platelet aggregation and coagulation. Simulating clotting under flow in complex geometries is challenging due to multiple temporal and spatial scales and high computational cost. <i>clotFoam</i> is an open-source software developed in OpenFOAM that employs a continuum model of platelet advection, diffusion, and aggregation in a dynamic fluid environment and a simplified coagulation model with proteins that advect, diffuse, and react within the flu ...[more]
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