Obesity and alcoholic etiology as risk factors for multisystem organ failure in acute pancreatitis: Multinational study.

ABSTRACT:

Background

Multisystem organ failure (MSOF) is the most important determinant of mortality in acute pancreatitis (AP). Obesity and alcoholic etiology have been examined as potential risk factors for MSOF, but prior studies have not adequately elucidated their independent effects on the risk of MSOF.

Objective

We aimed to determine the adjusted effects of body mass index (BMI) and alcoholic etiology on the risk of MSOF in subjects with AP.

Methods

A prospective observational study of 22 centers from 10 countries was conducted. Patients admitted to an APPRENTICE consortium center with AP between August 2015 and January 2018 were enrolled. Multivariable logistic regression was used to estimate the adjusted effects of BMI, etiology, and other relevant covariates on the ri

SUBMITTER: Lee PJ 

PROVIDER: S-EPMC10165322 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature