Modelling the impact of interventions on imported, introduced and indigenous malaria infections in Zanzibar, Tanzania.

ABSTRACT: Malaria cases can be classified as imported, introduced or indigenous cases. The World Health Organization's definition of malaria elimination requires an area to demonstrate that no new indigenous cases have occurred in the last three years. Here, we present a stochastic metapopulation model of malaria transmission that distinguishes between imported, introduced and indigenous cases, and can be used to test the impact of new interventions in a setting with low transmission and ongoing case importation. We use human movement and malaria prevalence data from Zanzibar, Tanzania, to parameterise the model. We test increasing the coverage of interventions such as reactive case detection; implementing new interventions including reactive drug administration and treatment of infected travellers;

SUBMITTER: Das AM 

PROVIDER: S-EPMC10182017 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature