Central retina plays a decisive role in the suppression of pupillary escape.

ABSTRACT:

Purpose

To explore the pupil redilation during persistent light exposure (pupillary escape phenomenon) at the macula and periphery with monochromatic light stimuli.

Methods

Forty healthy subjects aged 18-64 years (24 females) were examined by chromatic pupil campimetry (CPC) using red and blue 4-s stimuli of 10° radius at the center and 20°-peripheral locations one per quadrant. One glaucoma patient and one achromatopsia patient served as disease models. For statistical analyses, linear mixed-effects models were performed followed by post hoc t-tests.

Results

A distinct pupillary escape could be demonstrated peripherally (blue 0.099%*s, red 0.153%*s); at the central healthy retina, there was no relevant escape, neither for blue nor red stimulation. Comparing central v

SUBMITTER: Kelbsch C 

PROVIDER: S-EPMC10199107 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature