Thiophene-Derived Schiff Base Complexes: Synthesis, Characterization, Antimicrobial Properties, and Molecular Docking.

ABSTRACT: Novel thiophene-derived Schiff base ligand DE, where DE is (E)-N¹,N¹-diethyl-N²-(thiophen-2-ylmethylene)ethane-1,2-diamine, and the corresponding M(II) complexes, [M(DE)X₂] (M = Cu or Zn, X = Cl; M = Cd, X = Br), were prepared and structurally characterized. X-ray diffraction studies revealed that the geometry around the center of the M(II) complexes, [Zn(DE)Cl₂] and [Cd(DE)Br₂], could be best described as a distorted tetrahedral. In vitro antimicrobial screening of DE and its corresponding M(II) complexes, [M(DE)X₂], was performed. The complexes were more potent and showed higher activities against Escherichia coli, Stap

SUBMITTER: Nayab S 

PROVIDER: S-EPMC10210233 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature