The Rhodanese PspE Converts Thiosulfate to Cellular Sulfane Sulfur in Escherichia coli.

ABSTRACT: Hydrogen sulfide (H₂S) and its oxidation product zero-valent sulfur (S⁰) play important roles in animals, plants, and bacteria. Inside cells, S⁰ exists in various forms, including polysulfide and persulfide, which are collectively referred to as sulfane sulfur. Due to the known health benefits, the donors of H₂S and sulfane sulfur have been developed and tested. Among them, thiosulfate is a known H₂S and sulfane sulfur donor. We have previously reported that thiosulfate is an effective sulfane sulfur donor in Escherichia coli; however, it is unclear how it converts thiosulfate to cellular sulfane sulfur. In this study, we showed that one of the various rhodaneses, PspE, in E. coli was responsible for the conversion. After

SUBMITTER: Yu Q 

PROVIDER: S-EPMC10215317 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature