Association between IGFBP1 expression and cancer risk: A systematic review and meta-analysis.

ABSTRACT:

Background

The results regarding the association between insulin-like growth factor binding protein 1 (IGFBP1) expression and cancer risk were controversial. We performed a meta-analysis to provide novel evidence on relationship between IGFBP1 expression and cancer risk.

Methods

PubMed, Embase, Cochrane library and Web of science were searched for relevant cohort and case-control studies exploring the relationship between IGFBP1 expression and cancer risk. Odds ratios (ORs) were pooled in this meta-analysis using random model. Subgroup analyses were performed based on ethnicity, tumor types, publication year, study type, Newcastle-Ottawa Scale (NOS) score and sex.

Results

A total of 27 studies including 16 cohort and 11 case-control studies were identified by literatu

SUBMITTER: Zhang B 

PROVIDER: S-EPMC10220379 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature