Effects of 2 modes of positive pressure ventilation on respiratory mechanics and gas exchange in foals.

ABSTRACT:

Background

Continuous positive airway pressure (CPAP) and pressure support ventilation (PSV) can improve respiratory mechanics and gas exchange, but different airway pressures have not been compared in foals.

Hypothesis/objectives

Assess the effect of different airway pressures during CPAP and PSV have on respiratory function in healthy foals with pharmacologically induced respiratory insufficiency. We hypothesized that increased airway pressures would improve respiratory mechanics and increased positive end-expiratory pressure (PEEP) would be associated with hypercapnia.

Animals

Six healthy foals from a university teaching herd.

Methods

A prospective, 2-phase, 2-treatment, randomized cross-over study design was used to evaluate sequential interventions in seda

SUBMITTER: Raidal SL 

PROVIDER: S-EPMC10229351 | biostudies-literature | 2023 May-Jun

REPOSITORIES: biostudies-literature