Adjuvant endocrine therapy non-initiation and non-persistence in young women with early-stage breast cancer.

ABSTRACT:

Purpose

Characterizing oral adjuvant endocrine therapy (ET) non-initiation and non-persistence in young women with breast cancer can inform strategies to improve overall adherence in this population.

Methods

We identified 693 women with hormone receptor-positive, stage I-III breast cancer enrolled in a cohort of women diagnosed with breast cancer at age ≤ 40 years. Women were classified as non-initiators if they did not report taking ET in the 18 months after diagnosis. Women who initiated but did not report taking ET subsequently (through 5-year post-diagnosis) were categorized as non-persistent. We assessed ET decision-making and used logistic regression to identify factors associated with non-initiation/non-persistence and to evaluate the association between non-persisten

SUBMITTER: Rosenberg SM 

PROVIDER: S-EPMC10233447 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature