The Association between Frailty and Dementia-Free and Physical Disability-Free Survival in Community-Dwelling Older Adults.

ABSTRACT:

Introduction

Frailty is a common geriatric syndrome that adversely impacts health outcomes. This study examined correlates of physical frailty in healthy community-dwelling older adults and studied the effect of frailty on disability-free survival (DFS), defined as survival free of independence-limiting physical disability or dementia.

Methods

This is a post hoc analysis of 19,114 community-dwelling older adults (median age: 74.0 years, interquartile range or IQR: 6.1 years) from Australia and the USA enrolled in the "ASPirin in Reducing Events in the Elderly (ASPREE)" clinical trial. Frailty was assessed using a modified Fried phenotype and a deficit accumulation frailty index (FI) utilizing a ratio score derived from 66 items. Multinomial logistic regression was used to ex

SUBMITTER: Ekram ARMS 

PROVIDER: S-EPMC10238577 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature