Chapare Hemorrhagic Fever and Virus Detection in Rodents in Bolivia in 2019.

ABSTRACT:

Background

In June 2019, the Bolivian Ministry of Health reported a cluster of cases of hemorrhagic fever that started in the municipality of Caranavi and expanded to La Paz. The cause of these cases was unknown.

Methods

We obtained samples for next-generation sequencing and virus isolation. Human and rodent specimens were tested by means of virus-specific real-time quantitative reverse-transcriptase-polymerase-chain-reaction assays, next-generation sequencing, and virus isolation.

Results

Nine cases of hemorrhagic fever were identified; four of the patients with this illness died. The etiologic agent was identified as Mammarenavirus Chapare mammarenavirus, or Chapare virus (CHAPV), which causes Chapare hemorrhagic fever (CHHF). Probable nosocomial transmission

SUBMITTER: Loayza Mafayle R 

PROVIDER: S-EPMC10245337 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature