Unknown

Dataset Information

0

Precision chemical heating for diagnostic devices.


ABSTRACT: Decoupling nucleic acid amplification assays from infrastructure requirements such as grid electricity is critical for providing effective diagnosis and treatment at the point of care in low-resource settings. Here, we outline a complete strategy for the design of electricity-free precision heaters compatible with medical diagnostic applications requiring isothermal conditions, including nucleic acid amplification and lysis. Low-cost, highly energy dense components with better end-of-life disposal options than conventional batteries are proposed as an alternative to conventional heating methods to satisfy the unique needs of point of care use.

SUBMITTER: Buser JR 

PROVIDER: S-EPMC10249953 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature

altmetric image

Publications

Precision chemical heating for diagnostic devices.

Buser J R JR   Diesburg S S   Singleton J J   Guelig D D   Bishop J D JD   Zentner C C   Burton R R   LaBarre P P   Yager P P   Weigl B H BH  

Lab on a chip 20151201 23


Decoupling nucleic acid amplification assays from infrastructure requirements such as grid electricity is critical for providing effective diagnosis and treatment at the point of care in low-resource settings. Here, we outline a complete strategy for the design of electricity-free precision heaters compatible with medical diagnostic applications requiring isothermal conditions, including nucleic acid amplification and lysis. Low-cost, highly energy dense components with better end-of-life dispos  ...[more]

Similar Datasets

| S-EPMC4899688 | biostudies-literature
| S-EPMC10386938 | biostudies-literature
| S-EPMC7266111 | biostudies-literature
| S-EPMC5382709 | biostudies-literature
| S-EPMC3635774 | biostudies-other
2019-02-27 | GSE127208 | GEO
| S-EPMC9314691 | biostudies-literature
| S-EPMC10847440 | biostudies-literature
| S-EPMC11760603 | biostudies-literature
| S-EPMC4792951 | biostudies-literature