Progression of Kidney Disease in Kidney Transplant Recipients With a Failing Graft: A Matched Cohort Study.

ABSTRACT:

Background

Few studies have assessed outcomes in transplant recipients with failing grafts as most studies have focused on outcomes after graft loss.

Objective

To determine whether renal function declines faster in kidney transplant recipients with a failing graft than in people with chronic kidney disease of their native kidneys.

Design

Retrospective cohort study.

Setting

Alberta, Canada (2002-2019).

Patients

We identified kidney transplant recipients with a failing graft (2 estimated glomerular filtration rate [eGFR] measurements 15-30 mL/min/1.73 m² ≥90 days apart).

Measurements

We compared the change in eGFR over time (eGFR with 95% confidence limits, _LCLeGFR_UCL) and the competing risks of kidney failure and de

SUBMITTER: Lam NN 

PROVIDER: S-EPMC10259097 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature