Global, regional, and national trends in mesothelioma burden from 1990 to 2019 and the predictions for the next two decades.

ABSTRACT:

Objectives

We aimed to analyze the secular trends in mesothelioma burden, the effect of age, period, and birth cohort, and project the global burden over time.

Material and methods

Based on the mesothelioma incidence, mortality, and Disability-Adjusted Life Years (DALYs) data from 1990 to 2019 in Global Burden of Diseases (GBD) database, the annual percentage change (APC) and average annual percent change (AAPC), calculated from joinpoint regression model, was used to describe the burden trends. An age-period-cohort model was utilized to disentangle age, period, and birth cohort effects on mesothelioma incidence and mortality trends. The mesothelioma burden was projected by the Bayesian age-period-cohort (BAPC) model.

Results

Globally, there were the significant decli

SUBMITTER: Zhu W 

PROVIDER: S-EPMC10272494 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature