Central-positive complexes in ECT-induced seizures: Possible evidence for thalamocortical mechanisms.

ABSTRACT:

Objective

Central-positive complexes (CPCs) are elicited during electroconvulsive therapy (ECT) as generalized high-amplitude waveforms with maximum positive voltage over the vertex. While these complexes have been qualitatively assessed in previous literature, quantitative analyses are lacking. This study aims to characterize CPCs across temporal, spatial, and spectral domains.

Methods

High-density 64-electrode electroencephalogram (EEG) recordings during 50 seizures acquired from 11 patients undergoing right unilateral ECT allowed for evaluation of spatiotemporal characteristics of CPCs via source localization and spectral analysis.

Results

Peak-amplitude CPC scalp topology was consistent across seizures, showing maximal positive polarity over the midline fronto-cen

SUBMITTER: Huels ER 

PROVIDER: S-EPMC10273093 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature