Increasing Area Deprivation Index negatively impacts ovarian cancer survival.

ABSTRACT:

Introduction

While individual-level measures of socioeconomic status have been well-studied in relation to ovarian cancer survival, no studies to date have examined both state and national-level Area Deprivation Indices (ADIs), which incorporate neighborhood affluence and resources.

Methods

We abstracted clinical data from medical records for ovarian cancer cases from the Vanderbilt University Medical Center and obtained ADIs from the Neighborhood Atlas®. Associations with clinical characteristics were assessed with Spearman correlations and Kruskal-Wallis tests; associations with progression-free survival (PFS) and overall survival (OS) were assessed with Cox proportional-hazards regression.

Results

Among 184 cases, state and national ADIs were highly correlated, but

SUBMITTER: Hufnagel DH 

PROVIDER: S-EPMC10310307 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature