Influenza vaccination during pregnancy and risk of selected major structural noncardiac birth defects, National Birth Defects Prevention Study 2006-2011.

ABSTRACT:

Purpose

To assess associations between influenza vaccination during etiologically-relevant windows and selected major structural non-cardiac birth defects.

Study design

We analyzed data from the National Birth Defects Prevention Study, a multisite, population-based case-control study, for 8233 case children diagnosed with a birth defect and 4937 control children without a birth defect with delivery dates during 2006-2011. For all analyses except for neural tube defects (NTDs), we classified mothers who reported influenza vaccination 1 month before through the third pregnancy month as exposed; the exposure window for NTDs was 1 month before through the first pregnancy month. For defects with five or more exposed case children, we used logistic regression to estimate propensit

SUBMITTER: Palmsten K 

PROVIDER: S-EPMC10331487 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature