Detection of Bartonella henselae DNA in the blood of patients with livedoid vasculopathy.

ABSTRACT:

Background

Livedoid vasculopathy (LV) manifests as ulcers and atrophic white scars on the lower extremities. The main known etiopathogenesis is hypercoagulability with thrombus formation, followed by inflammation. Thrombophilia, collagen and myeloproliferative diseases may induce LV, but the idiopathic (primary) form predominates. Bartonella spp. may cause intra-endothelial infection and skin manifestations caused by these bacteria may be diverse, including leukocytoclastic vasculitis and ulcers.

Objective

The aim of this study was to investigate the presence of bacteremia by Bartonella spp. in patients with difficult-to-control chronic ulcers diagnosed as primary LV.

Methods

Questionnaires and molecular tests (conventional PCR, nested PCR and real-time PCR) were appl

SUBMITTER: Drummond MR 

PROVIDER: S-EPMC10334358 | biostudies-literature | 2023 Jul-Aug

REPOSITORIES: biostudies-literature