Cost-effectiveness of immediate total-body CT in patients with severe trauma (REACT-2 trial).

ABSTRACT:

Background

The effect of immediate total-body CT (iTBCT) on health economic aspects in patients with severe trauma is an underreported issue. This study determined the cost-effectiveness of iTBCT compared with conventional radiological imaging with selective CT (standard work-up (STWU)) during the initial trauma evaluation.

Methods

In this multicentre RCT, adult patients with a high suspicion of severe injury were randomized in-hospital to iTBCT or STWU. Hospital healthcare costs were determined for the first 6 months after the injury. The probability of iTBCT being cost-effective was calculated for various levels of willingness-to-pay per extra patient alive.

Results

A total of 928 Dutch patients with complete clinical follow-up were included. Mean costs of hospital

SUBMITTER: Treskes K 

PROVIDER: S-EPMC10364909 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature