Metabolic phenotyping of pilomotor seizures in autoimmune encephalitis.

ABSTRACT:

Objectives

Ictal piloerection (IP) is an uncommon symptom in focal epilepsy and is associated with autoimmune encephalitis (AE). However, the networks involved in AE-associated IP are still unclear. To have a better understanding of IP underlying mechanisms, the current study investigated whole-brain metabolic networks for the analysis of AE-associated IP.

Methods

Patients with AE and IP diagnosed at our Institute between 2018 and 2022 were selected. We then investigated the brain regions associated with AE-associated IP using positron emission tomography (PET). Anatomometabolic changes (interictal ¹⁸ F fluorodeoxyglucose PET) in AE patients with IP were compared with those of AE patients of similar age without IP (p-voxel <0.001, uncorrected).

Results

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SUBMITTER: Sun Y 

PROVIDER: S-EPMC10401145 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature