Prenatal exposure to air pollution is associated with structural changes in the neonatal brain.

ABSTRACT:

Background

Prenatal exposure to air pollution is associated with adverse neurologic consequences in childhood. However, the relationship between in utero exposure to air pollution and neonatal brain development is unclear.

Methods

We modelled maternal exposure to nitrogen dioxide (NO₂) and particulate matter (PM_2.5 and PM₁₀) at postcode level between date of conception to date of birth and studied the effect of prenatal air pollution exposure on neonatal brain morphology in 469 (207 male) healthy neonates, with gestational age of ≥36 weeks. Infants underwent MR neuroimaging at 3 Tesla at 41.29 (36.71-45.14) weeks post-menstrual age (PMA) as part of the developing human connectome project (dHCP). Single pollutant linear regression and canonica

SUBMITTER: Bos B 

PROVIDER: S-EPMC10410199 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature