Time trends in perinatal outcomes among HIV-positive pregnant women in Northern Tanzania: A registry-based study.

ABSTRACT:

Introduction

Maternal HIV infection is associated with increased risk of having a preterm delivery, low birth weight baby, small for gestational age baby and stillbirth. Maternal use of combination antiretroviral treatment is also associated with preterm delivery and low birth weight, although the effects vary by the type of drugs and timing of initiation.

Objective

To examine time trends in adverse perinatal outcomes among HIV-positive compared with HIV-negative women.

Design

Registry-based cohort study.

Setting

Northern Tanzania, 2000-2018.

Study sample

Mother-baby pairs of singleton deliveries (n = 41 156).

Methods

Perinatal outcomes of HIV-positive women were compared with HIV-negative women during time periods representing shifts in preventio

SUBMITTER: Rebnord T 

PROVIDER: S-EPMC10414606 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature