Differences in the distribution of hemoglobin variants according to the geographic regions in a Colombian population.

ABSTRACT:

Introduction

Colombia has been subject to intense genetic and cultural currents due to its geographical location. Hemoglobinopathies are the most common recessive diseases found worldwide and represent an important public health problem, according to the region and ancestry of each country.

Objectives

To evaluate the frequency of hemoglobin variants according to the geographical region in a population group adjusted to sex and age in Colombia.

Methods

This was a descriptive retrospective study of hemoglobin variants performed by electrophoresis in patients treated at and/or referred to specialized care institutions in Bogota, Colombia between January 2009 and December 2020.

Results

A total of 2,224 results were analyzed, 48.4% male and 51.5% female; 63.3% of pa

SUBMITTER: Vargas-Hernandez DA 

PROVIDER: S-EPMC10433307 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature