Comparison of Veno-arterial Extracorporeal Membrane Oxygenation Configurations for Patients Listed for Heart Transplantation.

ABSTRACT:

Background and objectives

Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) as a bridge to eventual heart transplantation (HT) is increasingly used worldwide. However, the effect of different VA-ECMO types on HT outcomes remains unclear.

Methods

This was a retrospective observational study of 111 patients receiving VA-ECMO and awaiting HT. We assessed 3 ECMO configuration groups: peripheral (n=76), central (n=12), and peripheral to central ECMO conversion (n=23). Cox proportional hazards regression and landmark analysis were conducted to analyze the effect of the ECMO configuration on HT and in-hospital mortality rates. We also evaluated adverse events during ECMO support.

Results

HT was performed in the peripheral (n=48, 63.2%), central (n=10, 83.3%), and c

SUBMITTER: Hong JA 

PROVIDER: S-EPMC10435828 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature