Orthohantavirus infections in humans and rodents in the Yichun region, China, from 2016 to 2021.

ABSTRACT:

Background

Rodents are the predominant natural hosts of orthohantavirus and the source of human infection, hemorrhagic fever with renal syndrome (HFRS) caused by orthohantavirus is a severe public health problem in the Yichun region, Jiangxi Province, China. However, little information is known about the infection of orthohantavirus in humans and rodents, and the genetic characteristics of the epidemic orthohantavirus in the region.

Methods

The clinical data of HFRS cases in 2016-2021 was analyzed. Virus infection in rodents was analyzed by orthohantavirus antigen detection using immunofluorescent assay, and the species of orthohantaviruses in rodents and patients were identified by real-time RT-PCR and gene sequencing. The S and M segments of orthohantaviruses from rodents

SUBMITTER: Liu SW 

PROVIDER: S-EPMC10437993 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature