Plasma Transfusion and Procoagulant Product Administration in Extracorporeal Membrane Oxygenation: A Secondary Analysis of an International Observational Study on Current Practices.

ABSTRACT:

Objectives

To achieve optimal hemostatic balance in patients on extracorporeal membrane oxygenation (ECMO), a liberal transfusion practice is currently applied despite clear evidence. We aimed to give an overview of the current use of plasma, fibrinogen concentrate, tranexamic acid (TXA), and prothrombin complex concentrate (PCC) in patients on ECMO.

Design

A prespecified subanalysis of a multicenter retrospective study. Venovenous (VV)-ECMO and venoarterial (VA)-ECMO are analyzed as separate populations, comparing patients with and without bleeding and with and without thrombotic complications.

Setting

Sixteen international ICUs.

Patients

Adult patients on VA-ECMO or VV-ECMO.

Interventions

None.

Measurements and main results

Of 420 VA-ECMO patien

SUBMITTER: van Haeren MMT 

PROVIDER: S-EPMC10443757 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature