A systematic review of psychosocial functioning changes after gender-affirming hormone therapy among transgender people.

ABSTRACT: This systematic review assessed the state and quality of evidence for effects of gender-affirming hormone therapy on psychosocial functioning. Forty-six relevant journal articles (six qualitative, 21 cross-sectional, 19 prospective cohort) were identified. Gender-affirming hormone therapy was consistently found to reduce depressive symptoms and psychological distress. Evidence for quality of life was inconsistent, with some trends suggesting improvements. There was some evidence of affective changes differing for those on masculinizing versus feminizing hormone therapy. Results for self-mastery effects were ambiguous, with some studies suggesting greater anger expression, particularly among those on masculinizing hormone therapy, but no increase in anger intensity. There were some trends t

SUBMITTER: Doyle DM 

PROVIDER: S-EPMC10444622 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature