Early versus Delayed Surgery in Patients with Left-Sided Infective Endocarditis and Stroke.

ABSTRACT:

Background

Timing of surgery remains controversial in patients with infective endocarditis and stroke. Guidelines on infective endocarditis suggest delaying surgery for up to 4 weeks. However, with early heart failure due to progression of the infection or recurrent septic embolism, urgent surgery becomes imperative.

Methods

Out of 688 patients who were surgically treated for left-sided infective endocarditis, 187 presented with preoperative neurological events. The date of cerebral stroke onset was documented in 147 patients. The patients were stratified according to timing of surgery: 61 in the early group (0-7 days) vs. 86 in the delayed group (>7 days). Postoperative neurological outcome was assessed by the modified Rankin Scale.

Results

Preoperative sepsis was mo

SUBMITTER: Kremer J 

PROVIDER: S-EPMC10455129 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature