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ABSTRACT: Purpose
To report the progression of patients diagnosed with birdshot chorioretinopathy (BSCR) initially treated with corticosteroids.Methods
We included 39 BSCR patients that were followed for ≥1 year. We analyzed their progression under treatment after 1, 3, 6 months, 1 year, and at the end of follow-up. In order to determine the efficiency of initial loading doses, patients were classified into two groups according to their initial treatment: methylprednisolone followed by prednisone (n = 28) and prednisone alone (n = 11).Results
At the end of follow-up, 31/39 (79.5%) patients had reached inflammation control. Thirteen out of 28 (46.4%) and 6/11 (54.5%) patients were treated exclusively with corticosteroids, and 18/19 (94.7%) of them had reached inflammation control at the end of follow-up; their mean (range) corticosteroid dose was 3.5 (0-10) mg/day.Conclusions
We found that the prolonged corticosteroid therapy treatment strategy resulted in inflammation control in half of BSCR patients. This control was maintained with low doses of cortisone, usually <5 mg/day.
SUBMITTER: Ferracci D
PROVIDER: S-EPMC10455668 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature
Ferracci Dino D Mathis Thibaud T Gavoille Antoine A Gerfaud-Valentin Mathieu M Bert Arthur A Hafidi Meriem M Denis Philippe P Loria Olivier O Kodjikian Laurent L Sève Pascal P
Journal of clinical medicine 20230814 16
<h4>Purpose</h4>To report the progression of patients diagnosed with birdshot chorioretinopathy (BSCR) initially treated with corticosteroids.<h4>Methods</h4>We included 39 BSCR patients that were followed for ≥1 year. We analyzed their progression under treatment after 1, 3, 6 months, 1 year, and at the end of follow-up. In order to determine the efficiency of initial loading doses, patients were classified into two groups according to their initial treatment: methylprednisolone followed by pre ...[more]