Functional connectome fingerprinting and stability in multiple sclerosis.

ABSTRACT:

Background

Functional connectome fingerprinting can identify individuals based on their functional connectome. Previous studies relied mostly on short intervals between fMRI acquisitions.

Objective

This cohort study aimed to determine the stability of connectome-based identification and their underlying signatures in patients with multiple sclerosis and healthy individuals with long follow-up intervals.

Methods

We acquired resting-state fMRI in 70 patients with multiple sclerosis and 273 healthy individuals with long follow-up times (up to 4 and 9 years, respectively). Using functional connectome fingerprinting, we examined the stability of the connectome and additionally investigated which regions, connections and networks supported individual identification. Finally

SUBMITTER: Mantwill M 

PROVIDER: S-EPMC10460476 | biostudies-literature | 2023 Jul-Sep

REPOSITORIES: biostudies-literature