Aberrant oscillatory activity in neurofibromatosis type 1: an EEG study of resting state and working memory.

ABSTRACT:

Background

Neurofibromatosis type 1 (NF1) is a genetic neurodevelopmental disorder commonly associated with impaired cognitive function. Despite the well-explored functional roles of neural oscillations in neurotypical populations, only a limited number of studies have investigated oscillatory activity in the NF1 population.

Methods

We compared oscillatory spectral power and theta phase coherence in a paediatric sample with NF1 (N = 16; mean age: 13.03 years; female: n = 7) to an age/sex-matched typically developing control group (N = 16; mean age: 13.34 years; female: n = 7) using electroencephalography measured during rest and during working memory task performance.

Results

Relative to typically developing children, the NF1 group displayed higher resting state slow

SUBMITTER: Booth SJ 

PROVIDER: S-EPMC10463416 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature