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Neuroinflammation: A Common Pathway in Alzheimer's Disease and Epilepsy.


ABSTRACT:

Background

Neuroinflammation is an innate immunological response of the central nervous system that may be induced by a brain insult and chronic neurodegenerative conditions. Recent research has shown that neuroinflammation may contribute to the initiation of Alzheimer's disease (AD) pathogenesis and associated epileptogenesis.

Objective

This systematic review aimed to investigate the available literature on the shared molecular mechanisms of neuroinflammation in AD and epilepsy.

Methods

The search included in this systematic review was obtained from 5 established databases. A total of 2,760 articles were screened according to inclusion criteria. Articles related to the modulation of the inflammatory biomarkers commonly associated with the progression of AD and epilep

SUBMITTER: Liew Y 

PROVIDER: S-EPMC10473147 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature